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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NEK2 All Species: 40
Human Site: S96 Identified Species: 62.86
UniProt: P51955 Number Species: 14
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P51955 NP_002488.1 445 51763 S96 C E G G D L A S V I T K G T K
Chimpanzee Pan troglodytes XP_514178 522 59597 S173 C E G G D L A S V I T K G T K
Rhesus Macaque Macaca mulatta XP_001108740 445 51674 S96 C E G G D L A S V I T K G T K
Dog Lupus familis XP_537144 668 75595 S320 C E G G D L A S L I T K G T K
Cat Felis silvestris
Mouse Mus musculus O35942 443 51289 S96 C E G G D L A S V I S K G T K
Rat Rattus norvegicus XP_001055166 443 51340 S96 C E G G D L A S V I T K G T K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509538 499 57433 S150 C E G G D L A S L I T R C T K
Chicken Gallus gallus NP_001026221 444 51581 S96 C D G G D L A S L I A R C T R
Frog Xenopus laevis NP_001079490 442 52004 S96 C E G G D L A S L I A K C T K
Zebra Danio Brachydanio rerio Q90XC2 697 76523 S98 Y I Q K R C N S L L D E D T I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_572415 735 82962 Q107 C A G G D L A Q I V Q R A R S
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_786794 453 51921 S96 C E G G D L G S L I S K C K K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9CAU7 606 68016 N97 A E A I K K T N G V H F T E E
Baker's Yeast Sacchar. cerevisiae P22209 435 51185 Q113 C S R G D L S Q M I K H Y K Q
Red Bread Mold Neurospora crassa P48479 858 94329 R95 C G N G D L G R V I R N L I K
Conservation
Percent
Protein Identity: 100 85 98.4 62.5 N.A. 87.6 89.4 N.A. 69.7 77 73.9 25.8 N.A. 30.2 N.A. N.A. 54.3
Protein Similarity: 100 85 99.3 65.4 N.A. 94.1 95 N.A. 80.9 88.7 86.7 39 N.A. 44.3 N.A. N.A. 72.1
P-Site Identity: 100 100 100 93.3 N.A. 93.3 100 N.A. 80 60 80 13.3 N.A. 40 N.A. N.A. 66.6
P-Site Similarity: 100 100 100 100 N.A. 100 100 N.A. 93.3 86.6 86.6 33.3 N.A. 60 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. 27.2 22.7 24.3
Protein Similarity: N.A. N.A. N.A. 44.8 43.8 36.1
P-Site Identity: N.A. N.A. N.A. 6.6 33.3 46.6
P-Site Similarity: N.A. N.A. N.A. 26.6 53.3 46.6
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 7 0 0 0 67 0 0 0 14 0 7 0 0 % A
% Cys: 87 0 0 0 0 7 0 0 0 0 0 0 27 0 0 % C
% Asp: 0 7 0 0 87 0 0 0 0 0 7 0 7 0 0 % D
% Glu: 0 67 0 0 0 0 0 0 0 0 0 7 0 7 7 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 0 % F
% Gly: 0 7 74 87 0 0 14 0 7 0 0 0 40 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 7 7 0 0 0 % H
% Ile: 0 7 0 7 0 0 0 0 7 80 0 0 0 7 7 % I
% Lys: 0 0 0 7 7 7 0 0 0 0 7 54 0 14 67 % K
% Leu: 0 0 0 0 0 87 0 0 40 7 0 0 7 0 0 % L
% Met: 0 0 0 0 0 0 0 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 7 0 0 0 7 7 0 0 0 7 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 7 0 0 0 0 14 0 0 7 0 0 0 7 % Q
% Arg: 0 0 7 0 7 0 0 7 0 0 7 20 0 7 7 % R
% Ser: 0 7 0 0 0 0 7 74 0 0 14 0 0 0 7 % S
% Thr: 0 0 0 0 0 0 7 0 0 0 40 0 7 67 0 % T
% Val: 0 0 0 0 0 0 0 0 40 14 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 0 0 0 0 0 0 0 0 0 7 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _